Pieris Pharmaceuticals (Nasdaq: PIRS) is a publicly-traded, clinical-stage biotechnology company with operations in Germany and the United States. Pieris specializes in the discovery and development of Anticalin® protein-based drugs to target validated disease pathways in a unique and transformative way. Our pipeline includes inhalable Anticalin proteins to treat respiratory diseases, immuno-oncology multi-specifics tailored for the tumor microenvironment, and a half-life-optimized Anticalin protein to treat anemia. Proprietary to Pieris, Anticalin proteins are a novel class of therapeutics validated in the clinic and by partnerships with leading pharmaceutical companies.

To strengthen our team in Hallbergmoos, we are looking for an experienced:

Scientist Protein Engineering & Technology Scouting (m/f/d)

Your Tasks

  • Design and generation of display libraries for Anticalin® selection
  • Proposal and execution of rational engineering strategies for Anticalin based mono- and multispecifics and fusion proteins
  • Responsible for bioinformatics and protein structure analyses
  • Proficient in implementing and applying software to design and optimize biologics such as MOE / Rosetta for protein modeling
  • Gathers and analyzes data to apply machine learning methods for protein engineering
  • Database management and support
  • Scouts for novel technologies
  • Collaborates with external industrial and academic partners

Our Requirements

  • PhD in life science or related area (biology, biochemistry, biophysics, biotechnology, bioinformatics) with 2+ years' experience
  • Solid knowledge in protein folding, aggregation, structure and dynamics
  • Deep understanding of techniques to study protein-protein interactions and state-of-the-art atomic-resolution structure elucidation tools such as NMR, X-ray crystallography, cryo-EM
  • Understanding of different display technologies as well as scaffold and antibody technologies
  • Expertise in Scripting (e.g. Python) and Molecular Dynamics is a definite plus
  • Knowledge of DNA sequence analysis tools such as Geneious will be beneficial
  • Cross-disciplinary orientated as well as reliable and flexible team player
  • Imaginative personality with self-sufficient and communicative appearance
  • Strong analytical and problem-solving skills
  • Precise and efficient operating
We are a fast-growing biotechnology company with approximately 130 employees at our sites in Freising (Greater Munich Area) and Boston (USA). We work in flat hierarchies with short decision-making paths and offer a working environment characterized by cooperation and innovation. Each of our employees participates in a bonus program based on the achievement of individual and company-wide goals. In addition, we offer each employee the opportunity to participate in a stock savings plan and a stock option program that allows employees to benefit directly from the company's success.
Numerous social benefits such as additional employer-financed company health insurance, free drinks, fruit baskets etc. as well as a bright, friendly and ultra-modern working environment with excellent technical equipment in our new company building in Hallbergmoos round off our overall package. Creative employee events take place several times a year, as team spirit is essential for us. The joint creation of an innovative and participative corporate culture is an important concern for us.